diff --git a/dialect/sql/builder.go b/dialect/sql/builder.go
index f8252775e..4d15f628f 100644
--- a/dialect/sql/builder.go
+++ b/dialect/sql/builder.go
@@ -1587,8 +1587,10 @@ func NotIn(col string, args ...interface{}) *Predicate {
 
 // NotIn appends the `Not IN` predicate.
 func (p *Predicate) NotIn(col string, args ...interface{}) *Predicate {
+	// If no arguments were provided, append the NOT FALSE constant, since
+	// we cannot apply "NOT IN ()". This will make this predicate truthy.
 	if len(args) == 0 {
-		return p
+		return Not(p.False())
 	}
 	return p.Append(func(b *Builder) {
 		b.Ident(col).WriteOp(OpNotIn)
diff --git a/dialect/sql/builder_test.go b/dialect/sql/builder_test.go
index 5688f421a..7c2899691 100644
--- a/dialect/sql/builder_test.go
+++ b/dialect/sql/builder_test.go
@@ -635,6 +635,16 @@ func TestBuilder(t *testing.T) {
 			wantQuery: `DELETE FROM "users" WHERE "parent_id" IS NULL AND "name" NOT IN ($1, $2)`,
 			wantArgs:  []interface{}{"foo", "bar"},
 		},
+		{
+			input: Delete("users").
+				Where(And(IsNull("parent_id"), In("name"))),
+			wantQuery: "DELETE FROM `users` WHERE `parent_id` IS NULL AND FALSE",
+		},
+		{
+			input: Delete("users").
+				Where(And(IsNull("parent_id"), NotIn("name"))),
+			wantQuery: "DELETE FROM `users` WHERE `parent_id` IS NULL AND (NOT (FALSE))",
+		},
 		{
 			input: Delete("users").
 				Where(And(False(), False())),